Desu Decoll Collagen Dura Matrix

Decoll Collagen Dura Matrix is a product designed to repair dura mater defects. It is manufactured from ultra-pure Type One collagen (contains >95.5% Type One collagen. It is supplied in sponge form and sterilised using Gamma irradiation.

The collagen Dural matrix acts as a barrier between the Dura and surrounding tissues, preventing peridural fibrous adhesions. It does not require suturing and is applied / placed directly. During the healing period of the tissue, the implanted matrix maintains its position and is fully absorbed into the structure.

Once in place, it accelerates the formation of new arachnoid membrane and pia mater. Its ergonomic and elastic structure allows it to quickly penetrate into complex single and double-sided tissue surfaces

Collagen-Based Dura Membrane for Neurosurgical Repair

In complex neurosurgical procedures, the integrity of the dura mater—the tough outermost membrane surrounding the brain and spinal cord—is often compromised. Whether due to trauma, tumor resection, congenital malformations, or spinal decompression surgeries, the restoration of dural continuity is critical to preventing cerebrospinal fluid (CSF) leakage, infection, and other serious complications. To address this need with precision and biological compatibility, Desu proudly presents DURASHEET™, an advanced collagen dura membrane engineered for high-performance dural repair and regeneration.

DURASHEET™ is a single-use, collagen-based implant made from ultra-pure, medical-grade type-1 bovine collagen, boasting a purity level of more than 95.5%. It serves as a biological substitute for the dura mater, delivering a natural and highly biocompatible scaffold that supports tissue integration, sealing, and healing in both cranial and spinal neurosurgical applications.

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Engineered for Clinical Excellence

One of the key differentiators of DURASHEET™ is its collagen composition. Type-1 collagen is the principal structural protein found in native dura, and its use in this product ensures biological familiarity, reduced immunogenicity, and optimal healing kinetics. Once implanted, the membrane gradually biodegrades, leaving behind a new layer of healthy, patient-derived connective tissue. This natural resorption process minimizes foreign body response and avoids the long-term complications associated with synthetic dural substitutes.

Thanks to its impermeable pore structure, DURASHEET™ provides exceptional fluid barrier properties, which significantly reduce the risk of CSF leakage. Unlike some competitive materials, it does not allow microfiltration through the membrane, thereby enhancing postoperative protection and promoting a dry surgical field.

Furthermore, DURASHEET™ does not require any pre-processing before implantation. The product is ready to use out of the package and can be quickly cut to size, shaped, and positioned according to the anatomical and surgical needs. This makes it an ideal choice in both elective and emergency procedures, where time efficiency and reliability are paramount.

Key Clinical Benefits

One of the key differentiators of DURASHEET™ is its collagen composition. DURASHEET™ is designed with a suite of features that elevate its performance across a wide range of neurosurgical interventions:

More Suturable: The collagen membrane is engineered to withstand suturing, making it an excellent choice for secure mechanical fixation to surrounding dura or fascia.

Superior Tensile Strength: DURASHEET™ is reinforced with high tensile strength properties, offering resistance to tearing or rupture during manipulation and placement.

Dual-Surface Usability: Both sides of the membrane are usable, reducing orientation errors and simplifying application, particularly in constrained operative fields.

High Absorption Capacity: The porous microstructure of the collagen allows for effective absorption of fluids, which aids in adhesion and healing.

These qualities make DURASHEET™ especially effective in high-pressure CSF environments and when used in conjunction with other neurosurgical closure materials such as fibrin glue, sealants, or tissue adhesives.

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Ideal Handling Characteristics

DURASHEET™ is easy to handle, suture, and secure. It maintains structural integrity when wet, remains flexible, and resists curling or fragmentation—common issues with many collagen-based materials. The sheet can be easily anchored with standard neurosurgical sutures or used as an onlay with biological adhesives.

Its white, non-transparent appearance allows for excellent visibility under the operating microscope, helping surgeons ensure precise placement and coverage. DURASHEET™ also supports stable manipulation with standard forceps and can be repositioned during application without structural compromise.